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Article

Modulation of Staphylococcus aureus Biofilm Matrix by Subinhibitory Concentrations of Clindamycin.

Antimicrobial agents and chemotherapy - 1 Oct 2016

Schilcher Katrin, Andreoni Federica, Dengler Haunreiter Vanina, Seidl Kati, Hasse Barbara, Zinkernagel Annelies S

Abstract excerpt

Staphylococcus aureus biofilms are extremely difficult to treat. They provide a protected niche for the bacteria, rendering them highly recalcitrant toward host defenses as well as antibiotic treatment. Bacteria within a biofilm are shielded from the immune system by the formation of an extracellular polymeric matrix, composed of polysaccharides, extracellular DNA (eDNA), and proteins. Many antibiotics do not...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27458233
DOI: 10.1128/AAC.00463-16
PMCID: PMC5038281

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