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Article

A chemosensory system that regulates biofilm formation through modulation of cyclic diguanylate levels.

Proceedings of the National Academy of Sciences of the United States of America - 4 Oct 2005

Hickman Jason W, Tifrea Delia F, Harwood Caroline S

Abstract excerpt

Pseudomonas aeruginosa causes chronic biofilm infections, and its ability to attach to surfaces and other cells is important for biofilm formation and maintenance. Mutations in a gene called wspF, part of a putative chemosensory signal-transduction operon, have been shown to result in cell aggregation and altered colony morphology. The WspF phenotypes depend on the presence of WspR, which is a member of a family...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclic GMP

Share to Gene Expression Regulation, Bacterial

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Share to Microscopy, Confocal

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Identifiers

PMID: 16186483
DOI: 10.1073/pnas.0507170102
PMCID: PMC1234902

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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