Article
[Polymorphisms screening of PON gene cluster].
Yi chuan = Hereditas - 1 Jul 2005
Wang Xiao-Ling, Fan Zhong-Jie, Huang Jian-Feng, Su Shao-Yong, Zhao Jian-Gong, Gu Dong-Feng
Abstract excerpt
To identify all putative functional polymorphisms of PON gene cluster in Chinese Han population. Common polymorphisms of PON1, PON2 and PON3 gene were identified by directly sequencing of genomic DNAs derived from 48 randomly selected patients with coronary heart disease. We designed PCR arrays to amplify regions up to about 1kb upstream from transcription-initiation sites, i.e., putative promoter regions, all...
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