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Article

A preliminary identification of PIN1 SNP linkage in patients with coronary heart disease from Handan, China.

Revista portuguesa de cardiologia - 1 Feb 2021

Wang Jing-Zhang, Zhang Yu-Hua, Bai Jing, Du Wen-Tao, Zhang Xiang-Yang

Abstract excerpt

Our aim was to perform an initial assessment of the polymorphic patterns of the PIN1 gene in patients with coronary heart disease (CHD). The PIN1-encoded protein (Pin1) suppresses eNOS-NO signaling and may impair cardiovascular function. Blood collection, DNA extraction, PCR amplification and gene sequencing were performed for thirty CHD participants living in central China, focusing on nine single nucleotide...

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PMID: 33358249
DOI: 10.1016/j.repc.2020.05.015

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