Article
[Detection of novel genetic markers of susceptibility to preeclampsia based on an analysis of the regulatory genes in the placental tissue].
Molekuliarnaia biologiia - 1 Jan 2000
Serebrova V N, Trifonova E A, Gabidulina T V, Bukharina I Yu, Agarkova T A, Evtushenko I D, Maksimova N R, Stepanov V A
Abstract excerpt
Regulatory single nucleotide polymorphisms (rSNPs) are the least-studied group of SNP; however, they play an essential role in the development of human pathology by altering the level of candidate genes expression. In this work, we analyzed 29 rSNPs in 17 new candidate genes associated with preeclampsia (PE) according to the analysis of the transcriptome in placental tissue. Three ethnic groups have been studied...
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