Article
[Association analysis between polymorphisms of PON gene cluster with coronary heart disease in Chinese].
Yi chuan xue bao = Acta genetica Sinica - 1 Jul 2005
Wang Xiao-Ling, Fan Zhong-Jie, Huang Jian-Feng, Su Shao-Yong, Zhao Jian-Gong, Gu Dong-Feng
Abstract excerpt
An extensive association analysis of PON gene cluster (PONs) with coronary heart disease (CHD) was performed in Chinese Han population. Eleven polymorphisms of PON1, PON2 and PON3 gene were investigated for association with CHD in 474 male patients and 475 controls. Univariate analyses showed the cases had significantly higher frequencies of PON1 192Q allele, 160R allele, -162A allele and PON2 311C allele than...
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