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Article

Role of the ATP-binding cassette transporter Abcg2 in the phenotype and function of cardiac side population cells.

Circulation research - 10 Oct 2008

Pfister Otmar, Oikonomopoulos Angelos, Sereti Konstantina-Ioanna, Sohn Regina L, Cullen Darragh, Fine Gabriel C, Mouquet Frédéric, Westerman Karen, Liao Ronglih

Abstract excerpt

Recently, the side population (SP) phenotype has been introduced as a reliable marker to identify subpopulations of cells with stem/progenitor cell properties in various tissues. We and others have identified SP cells from postmitotic tissues, including adult myocardium, in which they have been suggested to contribute to cellular regeneration following injury. SP cells are identified and characterized by a unique...

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Identifiers

PMID: 18787193
DOI: 10.1161/CIRCRESAHA.108.174615
PMCID: PMC3115759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Role of the ATP-binding cassette transporter Abcg2 in the phenotype and function of cardiac side population cells.PMID 18787193Read ↗

Cardiac Side Population CellsSemantic proximity Read ↗

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Side Population: Its Use in the Study of Cellular Heterogeneity and as a Potential Enrichment Tool for Rare Cell PopulationsSemantic proximity Read ↗

Side population/ABCG2-positive cells represent a heterogeneous group of haemopoietic cells: implications for the use of adult stem cells in transplantation and plasticity protocols.Semantic proximity Read ↗

The ATP-binding cassette transporter ABCG2 (BCRP), a marker for side population stem cells, is expressed in human heart.Semantic proximity Read ↗

[ABCG2/Bcrp1 transporter as phenotype markers and regulators of side population stem cells].Semantic proximity Read ↗

Age-Dependent Increase in Side Population Distribution Within Hematopoiesis: Implications for Our Understanding of the Mechanism of AgingSemantic proximity Read ↗

Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo.Semantic proximity Read ↗

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Prospective isolation of murine hematopoietic stem cells by expression of an Abcg2/GFP allele.Semantic proximity Read ↗

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