Article
Cellular and molecular regulation of skeletal muscle side population cells.
Stem cells (Dayton, Ohio) - 1 Jan 2004
Meeson Annette P, Hawke Thomas J, Graham Sarabeth, Jiang Nan, Elterman Joel, Hutcheson Kelley, Dimaio J Michael, Gallardo Teresa D, Garry Daniel J
Abstract excerpt
Muscle progenitor cells (satellite cells) function in the maintenance and repair of adult skeletal muscle. Side population (SP) cells are enriched in repopulating activity and also reside in adult skeletal muscle. In this study, we observed that Abcg2 is a determinant of the SP cell phenotype. Using reverse transcription polymerase chain reaction and immunohistochemical techniques, we localized Abcg2-expressing...
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