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Article

Loss of functional E-cadherin renders cells more resistant to the apoptotic agent taxol in vitro.

Experimental cell research - 15 Oct 2005

Ferreira Paulo, Oliveira Maria José, Beraldi Eliana, Mateus Ana Rita, Nakajima Takashi, Gleave Martin, Yokota Jun, Carneiro Fátima, Huntsman David, Seruca Raquel, Suriano Gianpaolo

Abstract excerpt

Experimental evidence supports a role for E-cadherin in suppressing invasion, metastasis, and proliferation. Germline mutations of the E-cadherin represent the genetic cause of hereditary diffuse gastric cancer (HDGC). In this type of tumor, isolated cancer cells permeate the basal membrane and paradoxically survive in the gastric wall in the absence of contact with neighbor epithelial cells or with the...

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Identifiers

PMID: 16112667
DOI: 10.1016/j.yexcr.2005.07.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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