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Article

Catalytic properties of cholinesterases: importance of tyrosine 109 in Drosophila protein.

Neuroreport - 1 Jan 1992

Mutero A, Pralavorio M, Simeon V, Fournier D

Abstract excerpt

Tyrosine 109 in the acetylcholinesterase sequence of Drosophila melanogaster corresponds to an aspartate in vertebrate cholinesterases. Mutation of this amino acid to a glycine in the human butyrylcholinesterase gives rise to the 'atypic' phenotype characterized by a reduced activity for charged compounds. We investigated the importance of tyrosine 109 in the Drosophila sequence by in vitro mutagenesis and its...

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PMID: 1611033
DOI: 10.1097/00001756-199201000-00010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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