Article
Mutagenesis of essential functional residues in acetylcholinesterase.
Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 1990
Gibney G, Camp S, Dionne M, MacPhee-Quigley K, Taylor P
Abstract excerpt
The cholinesterases are serine hydrolases that show no global similarities in sequence with either the trypsin or the subtilisin family of serine proteases. The cholinesterase superfamily includes several esterases with distinct functions and other proteins devoid of the catalytic serine and know...
Topics
- Acetylcholinesterase
- Animals
- Base Sequence
- Binding Sites
- Cell Line
- Cholinesterase Inhibitors
- Humans
- Kinetics
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Sequence Homology, Nucleic Acid
- Serine Endopeptidases
- Torpedo
- Transfection