Article
Drosophila melanogaster acetylcholinesterase: identification and expression of two mutations responsible for cold- and heat-sensitive phenotypes.
Molecular & general genetics : MGG - 15 Jun 1994
Mutero A, Bride J M, Pralavorio M, Fournier D
Abstract excerpt
AceIJ29 and AceIJ40 are cold- and heat-sensitive variants of the gene coding for acetylcholinesterase in Drosophila melanogaster. In the homozygous condition, these mutations are lethal when animals are raised at restrictive temperatures, i.e., below 23 degrees C for AceIJ29 or above 25 degrees C...
Topics
- Acetylcholinesterase
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Compartmentation
- Cloning, Molecular
- Cold Temperature
- Conserved Sequence
- Drosophila melanogaster
- Gene Expression Regulation, Enzymologic
- Hot Temperature
- Molecular Sequence Data
- Oocytes
- Phenotype
- Point Mutation
- Polymerase Chain Reaction
- Protein Folding
- Sequence Homology, Amino Acid