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Article

Dpp-responsive silencers are bound by a trimeric Mad-Medea complex.

The Journal of biological chemistry - 28 Oct 2005

Gao Sheng, Steffen Janet, Laughon Allen

Abstract excerpt

Transcriptional regulation by transforming growth factor-beta signaling is mediated by the Smad family of transcription factors. It is generally accepted that Smads must interact with other transcription factors to bind to their targets. However, recently it has been shown that a complex of the Drosophila Smad proteins, Mad and Medea, binds with high affinity to silencer elements that repress brinker and bag of...

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Source

Identifiers

PMID: 16109720
DOI: 10.1074/jbc.M506882200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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