Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of HBV gene variations on disease development and antiviral therapy for patients with chronic hepatitis B.

Hepatobiliary & pancreatic diseases international : HBPD INT - 1 Aug 2005

Chen Jin-Yu, Wang Lu-Wen, Sun Xiao-Mei, Gong Zuo-Jiong

Abstract excerpt

BACKGROUND: Viral variation may change pathogenicity, escape immunity, lead to persistence infection, and cause drug resistance against antiviral therapy. This study was undertaken to investigate the effects of HBV gene variation on the progression of disease and on the efficacy of antiviral therapy for patients with chronic hepatitis B(CHB). METHODS: Hepatitis B virus(HBV) gene mutational sites were detected...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents
Share to Disease Progression

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hepatitis B, Chronic

Share to Hepatitis B virus

Share to Interferon-alpha

Share to Lamivudine

Share to Reverse Transcriptase Inhibitors

Share to Severity of Illness Index

Source

Identifiers

PMID: 16109523

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of HBV gene variations on disease development and antiviral therapy for patients with chronic hepatitis B.PMID 16109523Read ↗

Key role of hepatitis B virus mutation in chronic hepatitis B development to hepatocellular carcinomaSemantic proximity Read ↗

[Emergence and clinical significance of YMDD and HBeAg-related mutations during lamivudine treatment].Semantic proximity Read ↗

[Study of gene chips in the detection of YMDD mutations in the region of HBV polymeras].Semantic proximity Read ↗

Correlation of the occurrence of YMDD mutations with HBV genotypes, HBV-DNA levels, and HBeAg status in Chinese patients with chronic hepatitis B during lamivudine treatment.Semantic proximity Read ↗

A complete genomic analysis of hepatitis B virus isolated from 516 Chinese patients with different clinical manifestations.Semantic proximity Read ↗

New Gene Variants Associated with the Risk of Chronic HBV Infection.Semantic proximity Read ↗

Early changes in quasispecies variant after antiviral therapy for chronic hepatitis B.Semantic proximity Read ↗

Impact of host gene polymorphisms on susceptibility to chronic hepatitis B virus infection.Semantic proximity Read ↗

Clinical and virological implications of A1846T and C1913A/G mutations of hepatitis B virus genome in severe liver diseases.Semantic proximity Read ↗

Naturally occurring mutations in the HBV core N-terminal domain reduce viral replication and HBeAg levelsSemantic proximity Read ↗

Large-scale viral genome analysis identifies novel clinical associations between hepatitis B virus and chronically infected patientsSemantic proximity Read ↗

Characterization of Full-Length Genomes of Hepatitis B Virus Quasispecies in Sera of Patients at Different Phases of Infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.