Article
[Study of gene chips in the detection of YMDD mutations in the region of HBV polymeras].
Zhonghua yi xue za zhi - 25 Mar 2003
Zhang Xin-hua, Zhang Yue-xin, Sun Li-ru, Wen Qian, Zhou Li-quan, Fan Guo-xia, Zhang Xin, Yang De-gang
Abstract excerpt
OBJECTIVE: To understand mutations of the HBV polymerase from the level of molecule-biology and to guide reasonably antiviral therapy in clinic and predict prognosis of the patients, the gene chips were applied to detect YMDD mutations for the serum samples with HBV DNA position before antiviral therapy. METHODS: The serum samples from 150 HBV DNA positive patients non-antiviral therapy were detected by nowly...
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