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Article

[Emergence and clinical significance of YMDD and HBeAg-related mutations during lamivudine treatment].

Zhonghua nei ke za zhi - 1 Feb 2004

Xu Dong, Tian De-ying, Wang Wei-hua, Chen Hong-yun, Xing Ming-you, Guo Wei, Song Pei-hui

Abstract excerpt

OBJECTIVE: To explore YMDD and HBeAg related mutations of hepatitis B virus and its clinical significance during lamivudine therapy. METHODS: From sera of chronic hepatitis B patients with 9 - 30 months lamivudine therapy, signal-base mutations of YMDD motif, G1896A, A1814C, A1762T and G1764A were analyzed by gene chips technique. RESULTS: In the 102 patients with 18 months in average of lamivudine treatment, 22...

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PMID: 15059411

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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