Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Brain-derived neurotrophic factor (Val66Met) genetic polymorphism is associated with substance abuse in males.

Brain research. Molecular brain research - 31 Oct 2005

Cheng Chih-Ya, Hong Chen-Jee, Yu Younger W-Y, Chen Tai-Jui, Wu Hung-Chi, Tsai Shih-Jen

Abstract excerpt

Data from animal studies and from genetic scans in humans suggest that brain-derived neurotrophic factor (BDNF), a member of the neurotrophic factor family, may be involved in the mechanisms underlying substance abuse. The present study tested the hypothesis that the BDNF-gene Val66Met polymorphism is associated with substance abuse. We studied this polymorphism in 103 methamphetamine- and 200 heroin-dependent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Brain-Derived Neurotrophic Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Heroin Dependence

Share to Methamphetamine

Share to Reference Values

Share to Sex Characteristics

Share to Substance-Related Disorders

Source

Identifiers

PMID: 16109452
DOI: 10.1016/j.molbrainres.2005.07.008

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Brain-derived neurotrophic factor (Val66Met) genetic polymorphism is associated with substance abuse in males.PMID 16109452Read ↗

Influence of brain-derived neurotrophic factor (val66met) genetic polymorphism on the ages of onset for heroin abuse in males.Semantic proximity Read ↗

Polymorphisms of brain-derived neurotrophic factor associated with heroin dependence.Semantic proximity Read ↗

BDNF gene polymorphisms and substance use disorders: a systematic review.Semantic proximity Read ↗

Association of the met66 allele of brain-derived neurotrophic factor (BDNF) with smoking.Semantic proximity Read ↗

An association between BDNF Val66Met polymorphism and impulsivity in methamphetamine abusers.Semantic proximity Read ↗

Association of brain-derived neurotrophic factor (Val66Met) genetic polymorphism with methamphetamine dependence in a Malaysian population.Semantic proximity Read ↗

Increased Risk-Taking Behaviour and Brain-Derived Neurotrophic Factor Val66Met Polymorphism Correlates to Decreased Serum Brain-Derived Neurotrophic Factor Level in Heroin Users.Semantic proximity Read ↗

The BDNF Val66Met polymorphism and plasma brain-derived neurotrophic factor levels in Han Chinese heroin-dependent patients.Semantic proximity Read ↗

The analysis of BDNF gene polymorphism haplotypes and impulsivity in methamphetamine abusers.Semantic proximity Read ↗

BDNF (Val66Met) genetic polymorphism is associated with vulnerability for methamphetamine dependence.Semantic proximity Read ↗

Brain-derived neurotrophic factor Val66Met and psychiatric disorders: meta-analysis of case-control studies confirm association to substance-related disorders, eating disorders, and schizophrenia.Semantic proximity Read ↗

BDNF Val(66)Met genotype is associated with drug-seeking phenotypes in heroin-dependent individuals: a pilot study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.