Article
Association of brain-derived neurotrophic factor (Val66Met) genetic polymorphism with methamphetamine dependence in a Malaysian population.
Brain research - 21 Oct 2010
Sim Maw Shin, Mohamed Zahurin, Hatim Ahmad, Rajagopal Vijaya Lejchimi, Habil Mohamad Hussain
Abstract excerpt
Methamphetamine is a highly addictive psychostimulant that has surged in popularity worldwide in the last decade. Brain-derived neurotrophic factor (BDNF), a member of the neurotrophic factor family, is widely expressed in the adult mammalian brain and plays an important role in the long-term survival, differentiation, and outgrowth of neurons. Previous studies suggested that the BDNF gene may be involved in the...
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