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Article

Association of the met66 allele of brain-derived neurotrophic factor (BDNF) with smoking.

Psychopharmacology - 1 Mar 2007

Lang Undine E, Sander Thomas, Lohoff Falk W, Hellweg Rainer, Bajbouj Malek, Winterer Georg, Gallinat Jürgen

Abstract excerpt

RATIONALE: It has been suggested that a susceptibility locus near the gene encoding the brain-derived neurotrophic factor (BDNF) contributes to individual differences in human addiction vulnerability. BDNF modulates several behaviors that are associated with addictive drugs, and upregulation of BDNF was found to be associated with several drugs of abuse such as amphetamine, cocaine, and nicotine. In this study,...

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Source

Identifiers

PMID: 17186223
DOI: 10.1007/s00213-006-0647-1

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Association of the met66 allele of brain-derived neurotrophic factor (BDNF) with smoking.PMID 17186223Read ↗

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The BDNF gene Val66Met polymorphism as a modifier of psychiatric disorder susceptibility: progress and controversy.Semantic proximity Read ↗

BDNF Val66Met polymorphism and serum concentrations of BDNF with smoking in Thai males.Semantic proximity Read ↗

Increase in serum brain-derived neurotrophic factor in met allele carriers of the BDNF Val66Met polymorphism is specific to males.Semantic proximity Read ↗

BDNF Val(66)Met genotype is associated with drug-seeking phenotypes in heroin-dependent individuals: a pilot study.Semantic proximity Read ↗

Brain-derived neurotrophic factor Val66Met and psychiatric disorders: meta-analysis of case-control studies confirm association to substance-related disorders, eating disorders, and schizophrenia.Semantic proximity Read ↗

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