Article
Mef2c factors are required for early but not late addition of cardiomyocytes to the ventricle.
Developmental biology - 1 Feb 2021
Kula-Alwar Duvaraka, Marber Michael S, Hughes Simon M, Hinits Yaniv
Abstract excerpt
During heart formation, the heart grows and undergoes dramatic morphogenesis to achieve efficient embryonic function. Both in fish and amniotes, much of the growth occurring after initial heart tube formation arises from second heart field (SHF)-derived progenitor cell addition to the arterial pole, allowing chamber formation. In zebrafish, this process has been extensively studied during embryonic life, but it...
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