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Article

FAPP2 is involved in the transport of apical cargo in polarized MDCK cells.

The Journal of cell biology - 15 Aug 2005

Vieira Otilia V, Verkade Paul, Manninen Aki, Simons Kai

Abstract excerpt

Phosphatidylinositol-4-phosphate (PI(4)P) is the main phosphoinositide in the Golgi complex and has been reported to play a pleiotropic role in transport of cargo from the trans-Golgi network to the plasma membrane (PM) in polarized Madin-Darby canine kidney (MDCK) cells. Overexpression of the chimeric fluorescent protein encoding the pleckstrin homology domain, which is specific for PI(4)P, inhibited both apical...

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Identifiers

PMID: 16103222
DOI: 10.1083/jcb.200503078
PMCID: PMC2171512

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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