Article
Alpha-latrotoxin modulates the secretory machinery via receptor-mediated activation of protein kinase C.
Traffic (Copenhagen, Denmark) - 1 Sept 2005
Liu Jie, Wan Qunfang, Lin Xianguang, Zhu Hongliang, Volynski Kirill, Ushkaryov Yuri, Xu Tao
Abstract excerpt
The hypothesis whether alpha-latrotoxin (LTX) could directly regulate the secretory machinery was tested in pancreatic beta cells using combined techniques of membrane capacitance (Cm) measurement and Ca2+ uncaging. Employing ramp increase in [Ca2+]i to stimulate exocytosis, we found that LTX low...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
