Article
Pathways of T cell activation and terminal differentiation in chronic inflammation.
Current drug targets. Inflammation and allergy - 1 Jun 2005
Isomäki Pia, Clark Joanna M, Panesar Manvinder, Cope Andrew P
Abstract excerpt
Immune and inflammatory responses are governed by antigen-specific T cells, whose activation, differentiation and effector function are induced by signals delivered via the T cell antigen receptor (TCR) and by costimulatory and cytokine receptors. The molecular events leading to the activation of naïve T cells have been extensively studied and are well characterized. Much less is known about the molecular and...
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