Article
Co-expression of the CD45RA and CD45RO antigens on T lymphocytes in chronic arthritis.
Clinical and experimental immunology - 1 Jul 1994
Summers K L, O'Donnell J L, Hart D N
Abstract excerpt
The site of T lymphocyte activation in chronic arthritis is unknown. Peripheral blood (PB) lymphocytes from chronic arthritis patients are in a 'naive' or non-activated state, as defined by expression of the CD45RA antigen and lack of HLA class II expression. In contrast, most synovial fluid (SF)...
Topics
- Arthritis
- Cell Differentiation
- Chronic Disease
- Fluorescent Antibody Technique
- HLA-DR Antigens
- Humans
- Immunologic Memory
- Leukocyte Common Antigens
- Lymphocyte Activation
- Models, Biological
- Phenotype
- Synovial Fluid
- T-Lymphocytes