Article
Co-expression of the CD45RA and CD45RO antigens on T lymphocytes in chronic arthritis.
Clinical and experimental immunology - 1 Jul 1994
Summers K L, O'Donnell J L, Hart D N
Abstract excerpt
The site of T lymphocyte activation in chronic arthritis is unknown. Peripheral blood (PB) lymphocytes from chronic arthritis patients are in a 'naive' or non-activated state, as defined by expression of the CD45RA antigen and lack of HLA class II expression. In contrast, most synovial fluid (SF) T lymphocytes express a 'memory' or activated phenotype, as defined by the CD45RO antigen and high HLA class II...
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