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The mechanism of dendritic cell-T cell crosstalk in rheumatoid arthritis

5 Oct 2023

Abstract excerpt

Abstract Rheumatoid arthritis (RA) is a chronic inflammatory disease characterised by joint pain and swelling, synovial hyperplasia, cartilage damage, and bone destruction. The mechanisms of dendritic cell (DC) and T cell-mediated crosstalk have gradually become a focus of attention. DCs regulate the proliferation and differentiation of CD4 + T cell subtypes through different cytokines, surface molecules, and...

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PMID: 37798668
DOI: 10.1186/s13075-023-03159-8

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