Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fibrocyte and T cell interactions promote disease pathogenesis in rheumatoid arthritis.

Journal of autoimmunity - 1 May 2016

Galligan Carole L, Keystone Edward C, Fish Eleanor N

Abstract excerpt

Rheumatoid arthritis (RA) is a systemic autoimmune disease. We previously identified a circulating cell population, fibrocytes, which is activated early in disease. As RA is characterized by the formation of autoantibodies and autoreactive T cells, which often precede symptom onset, the objective of these studies was to characterize fibrocyte activation in the context of T cell activation. Multidimensional flow...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Biomarkers
Share to Cell Communication

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytokines

Share to Immunophenotyping

Share to Lymphocyte Activation

Share to Lymphocyte Count

Share to T-Lymphocyte Subsets

Source

Identifiers

PMID: 26948996
DOI: 10.1016/j.jaut.2016.02.008

Genes

FOXP3
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fibrocyte and T cell interactions promote disease pathogenesis in rheumatoid arthritis.PMID 26948996Read ↗

Multi-dimensional analysis identified rheumatoid arthritis-driving pathway in human T cellSemantic proximity Read ↗

Integrated Single Cell and Spatial Transcriptomics Reveal Autoreactive Differentiated B Cells in Joints of Early Rheumatoid ArthritisSemantic proximity Read ↗

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis.Semantic proximity Read ↗

The role of the synovial fibroblast in rheumatoid arthritis pathogenesisSemantic proximity Read ↗

Dynamic macrophage phenotypes in autoimmune and inflammatory rheumatic diseasesSemantic proximity Read ↗

Synovial fibroblasts: key players in rheumatoid arthritisSemantic proximity Read ↗

Type-1 interferon-driven innate and <i>GZMK</i> + CD8 T cell activation precedes subclinical joint inflammation when rheumatoid arthritis is imminentSemantic proximity Read ↗

Antifibrotics Modify B-Cell–Induced Fibroblast Migration and Activation in Patients with Idiopathic Pulmonary FibrosisSemantic proximity Read ↗

Natural killer-like B cells promote Th17 cell differentiation and exacerbate rheumatoid arthritisSemantic proximity Read ↗

Rheumatoid arthritis synovial fluid shows enrichment of T-cells producing GMCSF which are polyfunctional for TNFα and IFNγ.Semantic proximity Read ↗

Fibrocyte measurement in peripheral blood correlates with number of cultured mature fibrocytes in vitro and is a potential biomarker for interstitial lung disease in Rheumatoid Arthritis.Semantic proximity Read ↗

Circulating fibrocytes: a potent cell population in antigen-presenting and wound healing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.