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Article

Role of Th17 cells in human autoimmune arthritis.

Arthritis and rheumatism - 1 Oct 2010

Leipe Jan, Grunke Mathias, Dechant Claudia, Reindl Christiane, Kerzendorf Ulrike, Schulze-Koops Hendrik, Skapenko Alla

Abstract excerpt

OBJECTIVE: To delineate the role of Th17 cells in the pathogenesis of autoimmune arthritides. METHODS: Th17 cells were analyzed in well-defined homogeneous cohorts of patients with the prototypical autoimmune arthritides rheumatoid arthritis (RA) and psoriatic arthritis (PsA), grouped according to patients who had very early active RA (n = 36; mean disease duration 2.8 months, Disease Activity Score in 28 joints...

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Identifiers

PMID: 20583102
DOI: 10.1002/art.27622

Genes

RORC
CCR4
CCR6

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