Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The thymus and rheumatology: should we care?

Current opinion in rheumatology - 1 Mar 2016

Cosway Emilie, Anderson Graham, Garside Paul, Prendergast Catriona

Abstract excerpt

PURPOSE OF REVIEW: The purpose of this review is to discuss the mechanisms of central and peripheral tolerance in relation to T-cell mediated autoimmunity in rheumatoid arthritis (RA). RECENT FINDINGS: The well established association between major histocompatibility complex class II and RA has led us to understand that T cells, and the adaptive immune response, are important in the pathogenesis of disease. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Experimental
Share to Autoantigens
Share to Autoimmunity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dendritic Cells

Share to Immune Tolerance

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Share to T-Lymphocytes, Regulatory

Share to Thymus Gland

Source

Open in PubMed Open full text

Identifiers

PMID: 26751840
DOI: 10.1097/BOR.0000000000000251
PMCID: PMC4732010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The thymus and rheumatology: should we care?PMID 26751840Read ↗

Regulatory T cell function in autoimmune diseaseSemantic proximity Read ↗

One year in review: the pathogenesis of rheumatoid arthritis.Semantic proximity Read ↗

Function and Role of Regulatory T Cells in Rheumatoid Arthritis.Semantic proximity Read ↗

Immune tolerance and the prevention of autoimmune diseases essentially depend on thymic tissue homeostasisSemantic proximity Read ↗

Secondary and ectopic lymphoid tissue responses in rheumatoid arthritis: from inflammation to autoimmunity and tissue damage/remodeling.Semantic proximity Read ↗

Exploring the therapeutic potential of regulatory T cell in rheumatoid arthritis: Insights into subsets, markers, and signaling pathwaysSemantic proximity Read ↗

[Thymus function and autoimmunity].Semantic proximity Read ↗

CD8(+) T cells in human autoimmune arthritis: the unusual suspects.Semantic proximity Read ↗

Rheumatoid arthritis: ‘melting pot’ of T helper subsetsSemantic proximity Read ↗

Autoimmune regulator and self‐tolerance – molecular and clinical aspectsSemantic proximity Read ↗

Thymus and autoimmunitySemantic proximity Read ↗

Effector T cells in rheumatoid arthritis: Lessons from animal modelsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.