Article
Kinetic fluorescence-quenching detection assay for allele frequency estimation.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2005
Xiao Ming, Kwok Pui-Yan
Abstract excerpt
The analysis of human genetic variations, such as single-nucleotide polymorphisms (SNPs), has great applications in genome-wide association studies of complex genetic traits. We have developed an SNP genotyping method based on the primer extension assay with fluorescence quenching detection. The...
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