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Article

Kinetic fluorescence-quenching detection assay for allele frequency estimation.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2005

Xiao Ming, Kwok Pui-Yan

Abstract excerpt

The analysis of human genetic variations, such as single-nucleotide polymorphisms (SNPs), has great applications in genome-wide association studies of complex genetic traits. We have developed an SNP genotyping method based on the primer extension assay with fluorescence quenching detection. The template-directed dye-terminator incorporation with fluorescence quenching detection (FQ-TDI) assay is based on the...

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PMID: 16100403
DOI: 10.1385/1-59259-957-5:115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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