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Article

WRN gene 1367 Arg allele protects against development of type 2 diabetes mellitus.

Diabetes research and clinical practice - 1 Sept 2005

Hirai Masashi, Suzuki Susumu, Hinokio Yoshinori, Yamada Takahiro, Yoshizumi Shinsuke, Suzuki Chitose, Satoh Jo, Oka Yoshitomo

Abstract excerpt

Werner's syndrome is an autosomal recessive disease caused by mutation of the WRN gene, which may lead to DNA repair failure and acceleration of aging. A polymorphism at amino acid 1367 Cys (TTG)/Arg (CTG) reportedly reduces the risk of myocardial infarction in Japanese. We studied the possible i...

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Source

Identifiers

PMID: 16098926
DOI: 10.1016/j.diabres.2005.01.012

Genes

WRN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16098926-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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