Article
Retardation of removal of radiation-induced apoptotic cells in developing neural tubes in macrophage galactose-type C-type lectin-1-deficient mouse embryos.
Glycobiology - 1 Dec 2005
Yuita Hiroshi, Tsuiji Makoto, Tajika Yuki, Matsumoto Yoshihisa, Hirano Kazuya, Suzuki Norio, Irimura Tatsuro
Abstract excerpt
MGL1/CD301a is a C-type lectin that recognizes galactose and N-acetylgalactosamine as monosaccharides and is expressed on limited populations of macrophages and dendritic cells at least in adult mice. In this study, pregnant mice with Mgl1+/- genotype were mated with Mgl1+/- or Mgl1-/- genotype males, and the embryos were used to assess a hypothesis that this molecule plays an important role in the clearance of...
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