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Article

Association study of interleukin 2 (IL2) and IL4 with schizophrenia in a Japanese population.

European archives of psychiatry and clinical neuroscience - 1 Oct 2008

Watanabe Yuichiro, Nunokawa Ayako, Shibuya Masako, Kaneko Naoshi, Nawa Hiroyuki, Someya Toshiyuki

Abstract excerpt

Interleukin 2 (IL-2) and IL-4 are pleiotropic cytokines regulating Th1/Th2 balance and have a regulatory activity in brain function. Thus these cytokines have been implicated in the pathophysiology of schizophrenia. The latest studies provided controversial results regarding the genetic associati...

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PMID: 18574615
DOI: 10.1007/s00406-008-0813-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18574615-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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