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The value of interleukin-12B (p40) gene promoter polymorphism in patients with schizophrenia in a region of East Turkey.

Psychiatry and clinical neurosciences - 1 Jun 2008

Ozbey Ulku, Tug Esra, Kara Murat, Namli Mustafa

Abstract excerpt

AIMS: It has been hypothesized that the activation of the immune system may be involved in the neuropathological changes occurring in the central nervous system of schizophrenic patients. Cytokines play a key role in the activation of the immune system. Moreover, they strongly influence the dopaminergic, noradrenergic and serotonergic neurotransmission. To the best of our knowledge, in schizophrenic patients,...

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PMID: 18588591
DOI: 10.1111/j.1440-1819.2008.01798.x

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