Article
Neuronal development in the Drosophila retina: the sextra gene defines an inhibitory component in the developmental pathway of R7 photoreceptor cells.
Proceedings of the National Academy of Sciences of the United States of America - 15 Jun 1992
Rogge R, Cagan R, Majumdar A, Dulaney T, Banerjee U
Abstract excerpt
Mutations in a gene called sextra (sxt) have been isolated. Loss of one copy of sxt promotes R7 photoreceptor cell development in a genetically sensitized background, while loss of both copies results in precursors of non-neuronal cone cells transforming into R7 cells. The requirement for sxt function is cell-autonomous. The transformation of cone-cell precursors into R7 cells occurs independently of the...
Topics
- Animals
- Chromosome Mapping
- Drosophila
- Enhancer Elements, Genetic
- Genotype
- Microscopy, Electron
- Mutation
- Neurons
- Photoreceptor Cells
- Recombination, Genetic