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Article

Trefoil factor family-3 is associated with aggressive behavior of colon cancer cells.

Clinical & experimental metastasis - 1 Jan 2005

Yio Xianyang, Zhang Jie-yu, Babyatsky Mark, Chen Anli, Lin Jing, Fan Qui-Xiang, Werther J Lawrence, Itzkowitz Steven

Abstract excerpt

BACKGROUND AND AIM: Trefoil factor family 3 (TFF3) is expressed by intestinal epithelial cells and it mainly functions to protect the mucosa from injury. Expression of TFF3 has been correlated with a poor prognosis in patients with cancer, but little is known about whether TFF3 directly contributes to the malignant behavior of cancer cells. The present study was conducted to determine whether TFF3 expression...

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Source

Identifiers

PMID: 16086236
DOI: 10.1007/s10585-005-6615-z

Genes

TFF3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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