Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of trefoil factor 3 is decreased in colorectal cancer.

Oncology reports - 1 Jan 2021

Espinoza Ingrid, Agarwal Sumit, Reddy Amit, Shenoy Veena, Subramony Charulochana, Sakiyama Marcelo, Fair Logan, Poosarla Teja, Zhou Xinchun, Shannon Orr W, Lahr Christopher, Bae Sejong, Al Diffalha Sameer, Manne Upender, Gomez Christian R

Abstract excerpt

In colorectal cancer (CRC), high expression of trefoil factor 3 (TFF3) is associated with tumor progression and reduced patient survival; however, bioinformatics analyses of public 'omics' databases show low TFF3 expression in CRCs as compared to normal tissues. Thus, we examined TFF3 expression in CRCs and matching normal tissues to evaluate its role in CRC progression. TFF3 gene expression was characterized...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caveolin-1 and cellular processes

Share to Colorectal Neoplasms

Share to Computational Biology

Share to Galectins and Cancer Biology

Share to Mutation

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 33210724
DOI: 10.3892/or.2020.7829
PMCID: PMC7716703

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of trefoil factor 3 is decreased in colorectal cancer.PMID 33210724Read ↗

Trefoil factor 3: a novel serum marker identified by gene expression profiling in high-grade endometrial carcinomasSemantic proximity Read ↗

Trefoil factor family-3 is associated with aggressive behavior of colon cancer cells.Semantic proximity Read ↗

Downregulation of fibulin-3 gene by promoter methylation in colorectal cancer predicts adverse prognosisSemantic proximity Read ↗

CSF3 contributes to the invasive and metastatic phenotypes and associates with poor prognosis in patients with colorectal cancer via NF-κB signaling pathwaySemantic proximity Read ↗

Transcriptomic Profiling of Tumor-Infiltrating CD4+TIM-3+ T Cells Reveals Their Suppressive, Exhausted, and Metastatic Characteristics in Colorectal Cancer PatientsSemantic proximity Read ↗

CSF3 promotes colorectal cancer progression by activating p65/NF-κB signaling pathway and inducing an immunosuppressive microenvironmentSemantic proximity Read ↗

TUSC3 promotes colorectal cancer progression and epithelial-mesenchymal transition (EMT) through WNT/β-catenin and MAPK signalling.Semantic proximity Read ↗

Trefoil factor 1 gene alternations and expression in colorectal carcinomas.Semantic proximity Read ↗

TFF3 is a normal breast epithelial protein and is associated with differentiated phenotype in early breast cancer but predisposes to invasion and metastasis in advanced disease.Semantic proximity Read ↗

RUFY3 interaction with FOXK1 promotes invasion and metastasis in colorectal cancerSemantic proximity Read ↗

Mutations of p53 and K-ras correlate TF expression in human colorectal carcinomas: TF downregulation as a marker of poor prognosis.Semantic proximity Read ↗

Differential expression of Tim3 protein in colorectal cancer associated with MSI and Braf mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.