Article
Using progenitor strain information to identify quantitative trait nucleotides in outbred mice.
Genetics - 1 Oct 2005
Yalcin B, Flint J, Mott R
Abstract excerpt
We have developed a fast and economical strategy for dissecting the genetic architecture of quantitative trait loci at a molecular level. The method uses two pieces of information: mapping data from crosses that involve more than two inbred strains and sequence variants in the progenitor strains within the interval containing a quantitative trait locus (QTL). By testing whether the strain distribution pattern in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
