Article
A strategy for the integration of QTL, gene expression, and sequence analyses.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Nov 2003
Hitzemann Robert, Malmanger Barry, Reed Cheryl, Lawler Maureen, Hitzemann Barbara, Coulombe Shannon, Buck Kari, Rademacher Brooks, Walter Nicole, Polyakov Yekatrina, Sikela James, Gensler Brenda, Burgers Sonya, Williams Robert W, Manly Ken, Flint Jonathan, Talbot Christopher
Abstract excerpt
Although hundreds if not thousands of quantitative trait loci (QTL) have been described for a wide variety of complex traits, only a very small number of these QTLs have been reduced to quantitative trait genes (QTGs) and quantitative trait nucleotides (QTNs). A strategy, Multiple Cross Mapping (MCM), is described for detecting QTGs and QTNs that is based on leveraging the information contained within the...
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