Article
Lack of association of cathepsin D genetic polymorphism with Alzheimer's disease in Koreans.
Archives of gerontology and geriatrics - 1 Jan 2000
Jhoo Jin Hyeong, Park Woong Yang, Kim Ki Woong, Lee Kwang Hyuk, Lee Dong Young, Youn Jong Chul, Choo Il Han, Seo Jeong Sun, Woo Jong Inn
Abstract excerpt
Cathepsin D (CatD) is a good candidate susceptibility marker for Alzheimer's disease (AD), since it was found to be involved in the processing of the amyloid precursor protein and the formation of the hyperphosphorylated tau. And recently, a CatD genetic polymorphism was found to be associated with the risk of Alzheimer's disease (AD) in a German population. However, the CatD T-AD association has not been...
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