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Article

Non-replication of association between cathepsin D genotype and late onset Alzheimer disease.

American journal of medical genetics - 8 Mar 2001

Menzer G, Müller-Thomsen T, Meins W, Alberici A, Binetti G, Hock C, Nitsch R M, Stoppe G, Reiss J, Finckh U

Abstract excerpt

In two recent studies from Germany, a strong association was found between the allelic variant T of the amino acid substitution encoding polymorphism 224 C/T (A38V) in exon 2 of the cathepsin D gene (CTSD) and late onset Alzheimer disease (AD). Other studies from Europe and the USA revealed ambiguous results. Therefore, we performed an independent association study on CTSD and AD in a sample of 324 Caucasian...

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Source

Identifiers

PMID: 11304834
DOI: 10.1002/ajmg.1204

Genes

CTSD
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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