Article
[Relationship between the aldosterone synthase (CYP11B2)-344C/T polymorphism and small artery compliance].
Zhonghua xin xue guan bing za zhi - 1 Jul 2005
Li Xin-li, Liang Li-rong, Ni Chun-hui, Wang Zhen-zhen, Li Ai-ping, Liao Jing, Zhou Jian-wei, Cao Ke-jiang, Huang Jun
Abstract excerpt
OBJECTIVE: To investigate the relationship between the aldosterone synthase (CYP11B2)-344C/T polymorphism and small artery compliance (C(2)). METHODS: C(2) was measured by CVProfilor DO-2020 in 224 subjects, including 123 subjects with an abnormal C(2) and 101 normal controls. Genotypes of CYP11B2 were determined by polymerase chain reaction-based restriction fragment length polymorphism analysis. RESULTS: The...
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