Article
An automated genotyping system for analysis of HIV-1 and other microbial sequences.
Bioinformatics (Oxford, England) - 1 Oct 2005
de Oliveira Tulio, Deforche Koen, Cassol Sharon, Salminen Mika, Paraskevis Dimitris, Seebregts Chris, Snoeck Joe, van Rensburg Estrelita Janse, Wensing Annemarie M J, van de Vijver David A, Boucher Charles A, Camacho Ricardo, Vandamme Anne-Mieke
Abstract excerpt
MOTIVATION: Genetic analysis of HIV-1 is important not only for vaccine development, but also to guide treatment strategies, track the emergence of new viral variants and ensure that diagnostic assays are contemporary and fully optimized. However, most genotyping methods are laborious and complex, and involve the use of multiple software applications. Here, we describe the development of an automated genotyping...
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