Article
The role of subtyping methodologies in HIV surveillance and vaccine development: a systematic review and meta-analysis.
AIDS (London, England) - 1 May 2026
Williams Alexandria, Adungo Ferdinard, Ramirez Juan Luis, Oriol-Mathieu Valerie, Macartney Malcolm, Menon Sonia
Abstract excerpt
BACKGROUND: HIV genetic diversity has increased over time, with recombinant forms becoming more prevalent and complicating subtype classification and surveillance, particularly in low-and-middle income countries (LMICs). Accurate subtyping is critical for surveillance, vaccine design, and cure strategies, but its reliability depends on methodological choices - the genomic region sequenced, laboratory methods...
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