Article
Assessment of automated genotyping protocols as tools for surveillance of HIV-1 genetic diversity.
AIDS (London, England) - 13 Jul 2006
Gifford Robert, de Oliveira Tulio, Rambaut Andrew, Myers Richard E, Gale Catherine V, Dunn David, Shafer Robert, Vandamme Anne-Mieke, Kellam Paul, Pillay Deenan
Abstract excerpt
BACKGROUND: The routine use of drug resistance testing provides an abundant source of HIV-1 sequence data. However, it is not clear how reliable standard genotyping of these sequences is for describing HIV-1 genetic variation and for detecting novel genetic variants and epidemiological trends. OBJECTIVES: To compare assignment of HIV-1 resistance test sequences to reference strains across commonly used genotyping...
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