Article
Universal profiling of HIV-1 pol for genotypic study and resistance analysis across subtypes.
Antiviral therapy - 1 Jan 2011
Nie Ting, Detorio Mervi, Schinazi Raymond F
Abstract excerpt
BACKGROUND: The increased use of anti-HIV-1 treatments in developing countries primarily infected by non-B subtypes necessitates development of novel tools to assess susceptibility and resistance. HIV-1 genomes are highly polymorphic and present challenges for the development of universal protoco...
Topics
- Anti-HIV Agents
- Cloning, Molecular
- DNA Fingerprinting
- DNA Mutational Analysis
- DNA Primers
- DNA-Directed RNA Polymerases
- Drug Resistance, Viral
- Escherichia coli
- Genotype
- HIV Infections
- HIV-1
- Humans
- Mutation
- RNA, Viral
- Real-Time Polymerase Chain Reaction
- Reverse Transcriptase Polymerase Chain Reaction
- Viral Load
- Viral Proteins