Article
[Cytolytic activity by lymphokines (LAK activity) in chronic myeloid leukemia].
Medicina clinica - 10 Jun 1995
Cervantes F, Miller J S, McGlave P B
Abstract excerpt
BACKGROUND: Recent studies indicate that patients with chronic myeloid leukemia (CML) have a population of benign cytolytic cells (natural killer or NK) in their peripheral blood which may expand and activate in vitro in the presence of interleukin-2 (IL-2) leading to cytolytic cells activated by lymphokine or LAK cells (lymphokine-activated killer). METHODS: Thirteen patients with CML in the chronic phase of a...
Topics
- Adult
- Antibodies, Monoclonal
- Centrifugation, Density Gradient
- Cytotoxicity Tests, Immunologic
- Female
- Humans
- Killer Cells, Lymphokine-Activated
- Killer Cells, Natural
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Lymphocyte Subsets
