Article
Anti-leukemia potential of interleukin-2 activated natural killer cells after bone marrow transplantation for chronic myelogenous leukemia.
Blood - 1 Jun 1990
Hauch M, Gazzola M V, Small T, Bordignon C, Barnett L, Cunningham I, Castro-Malaspinia H, O'Reilly R J, Keever C A
Abstract excerpt
The anti-leukemia potential of natural killer (NK) cells has been evaluated in 40 patients transplanted for chronic myelogenous leukemia (CML) to determine whether differences in NK cell function were correlated with subsequent leukemic relapse. Cells from patients and their donors were tested in 51Cr release assays against fully allogeneic CML targets and against cultured K562 targets; cells from 26 patients...
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