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Article

Generation of adherent lymphokine activated killer (A-LAK) cells from patients with acute myelogenous leukaemia.

British journal of cancer - 1 Feb 1992

Sedlmayr P, Rabinowich H, Winkelstein A, Herberman R B, Whiteside T L

Abstract excerpt

Successful generation of adherent lymphokine-activated killer (A-LAK) cells, highly-enriched in CD3-CD56+ antitumour effector cells, from the peripheral blood of ten patients with acute myelogenous leukaemia (AML) is described. The AML patients were either untreated or in remission. In vitro proliferation of A-LAK cells in patients with AML was generally poor, unless the cells were cocultured with irradiated...

Topics

Cell Adhesion
Humans
Immunotherapy, Adoptive
Killer Cells, Lymphokine-Activated
Leukemia, Myeloid, Acute
Lymphocyte Activation
Phenotype

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1739621
DOI: 10.1038/bjc.1992.45
PMCID: PMC1977745

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1739621-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Generation of adherent lymphokine activated killer (A-LAK) cells from patients with acute myelogenous leukaemia.PMID 1739621Read ↗

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