Article
Mitochondrial genome polymorphisms associated with type-2 diabetes or obesity.
Mitochondrion - 1 Feb 2005
Guo Li-Jun, Oshida Yoshiharu, Fuku Noriyuki, Takeyasu Takeshi, Fujita Yasunori, Kurata Miyuki, Sato Yuzo, Ito Masafumi, Tanaka Masashi
Abstract excerpt
Although a strong correlation between type-2 diabetes and obesity has been found, no comparative analysis between diabetes and obesity has been performed with respect to mitochondrial DNA (mtDNA) polymorphisms. To test the hypothesis that certain mitochondrial single nucleotide polymorphisms (mtSNPs) might be associated with obesity or type-2 diabetes, we determined the entire sequences of the mitochondrial...
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