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Article

Drosophila Melted modulates FOXO and TOR activity.

Developmental cell - 1 Aug 2005

Teleman Aurelio A, Chen Ya-Wen, Cohen Stephen M

Abstract excerpt

The insulin/PI3K signaling pathway controls both tissue growth and metabolism. Here, we identify Melted as a new modulator of this pathway in Drosophila. Melted interacts with both Tsc1 and FOXO and can recruit these proteins to the cell membrane. We provide evidence that in the melted mutant, TO...

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Source

Identifiers

PMID: 16054033
DOI: 10.1016/j.devcel.2005.07.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16054033-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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